12 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp02466 | ChBac3.4 | RFRLPFRRPPIRIHPPPFYPPFRRFL | Goat | Cell necrosis; Inhibiting processes of protein synthesis; Damaging the mitochondrial membrane | TUNEL assay, Reactive oxygen intermediates (ROS) assay | A375 cells | Melanoma | Not found |
| dbacp02467 | ChBac3.4 | RFRLPFRRPPIRIHPPPFYPPFRRFL | Goat | Cell necrosis; Inhibiting processes of protein synthesis; Damaging the mitochondrial membrane | TUNEL assay, Reactive oxygen intermediates (ROS) assay | Not specified | Pancreatic cancer | Not found |
| dbacp02468 | ChBac3.4 | RFRLPFRRPPIRIHPPPFYPPFRRFL | Goat | Cell necrosis; Inhibiting processes of protein synthesis; Damaging the mitochondrial membrane | TUNEL assay, Reactive oxygen intermediates (ROS) assay | Not specified | Bladder cancer | Not found |
| dbacp02469 | ChBac3.4 | RFRLPFRRPPIRIHPPPFYPPFRRFL | Goat | Cell necrosis; Inhibiting processes of protein synthesis; Damaging the mitochondrial membrane | TUNEL assay, Reactive oxygen intermediates (ROS) assay | Not specified | Breast cancer | Not found |
| dbacp02470 | ChBac3.4 | RFRLPFRRPPIRIHPPPFYPPFRRFL | Goat | Cell necrosis; Inhibiting processes of protein synthesis; Damaging the mitochondrial membrane | TUNEL assay, Reactive oxygen intermediates (ROS) assay | Not specified | Ovarian cancer | Not found |
| dbacp02801 | Dolastatin 10 | 2-[[2-(dimethylamino)-3-methylbutanoyl]amino]-N-[3-methoxy-1-[2-[1-methoxy-2-methyl-3-oxo-3-[[2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutaNAmide | Wedge sea hare | Apoptosis inducing | TUNEL assay | DU-145 | Prostate cancer | IC50 : 0.5 nM |
| dbacp05009 | Okinawa Habu apoxin protein-1(OHAP-1) | ADDRNPLEECFRETDYEEFLEIARNGLKKT | Venom base | Inducing apoptosis | DNA gel electrophoresis assay,TUNEL assay, MTT assay | RBR17T | Glioma | IC50 : 2.1 ± 0.58 µg/ml |
| dbacp05010 | Okinawa Habu apoxin protein-1(OHAP-1) | ADDRNPLEECFRETDYEEFLEIARNGLKKT | Venom base | Inducing apoptosis | DNA gel electrophoresis assay,TUNEL assay, MTT assay | OHAP-1 | Glioma | IC50 : 1.9 ± 0.31 µg/ml |
| dbacp05011 | Okinawa Habu apoxin protein-1(OHAP-1) | ADDRNPLEECFRETDYEEFLEIARNGLKKT | Venom base | Inducing apoptosis | DNA gel electrophoresis assay,TUNEL assay, MTT assay | C6 | Glioma | IC50 : 2.48 ± 0.26 µg/ml |
| dbacp06192 | Tachyplesin I | KWCFRVCYRGICYRRCR | Hemocytes, Southeast Asia, Japanese horseshoe crab | Apoptosis inducing | Luciferase reporter assay, TUNEL assay | T167 | Squamous cell oral carcinoma | Not found |
| dbacp06193 | Tachyplesin I | KWCFRVCYRGICYRRCR | Hemocytes, Southeast Asia, Japanese horseshoe crab | Apoptosis inducing | Luciferase reporter assay, TUNEL assay | T-409 | Squamous cell oral carcinoma | Not found |
| dbacp08436 | Alpha-gliadin peptide p31-43 | LGQQQPFPPQQPY | Synthetic | Not Available | TUNEL assay | A-549 | Lung Cancer | Mean apoptotic rate = 36% at 200 μg/mL |