9 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp03419 | Interferon gamma (IFN-gamma) | MNYTSFILAFQLCAILGSSTYYCQAAFFKEIENLKEYFNASNPDVGDGGPLFLDILKNWKEDSDKKIIQSQIVSFYFKLFENLKDNQVIQKSMDTIKEDLFVKFFNSSTSKLEDFQKLIQIPVNDLKVQRKAISELIKVMNDLSPKANLRKRKRSQNPFRGRRALQ | Horse | Necrosis; Immunomodulatory activity | Not specified | Not found | Not found | Not found |
| dbacp03437 | Interferon gamma (IFN-gamma) | MNYTGYILAFQLCVILGSYGCNCQATLLKEIDNLKTYINATNSDVADGGTLFLDILKNWKEESDKKIIQSQVVSFYFKLFESLKDNQLIKSSMEAIKEDLSVKFFNSSSSKMEDFKKLIQIPVNDVKVQRKAISELFNVMKDLSPSSNLRKRKRSQGLFRGRRASK | Greater horseshoe bat | Immunomodulatory mechanisms | Not specified | Not found | Not found | Not found |
| dbacp05596 | Polyphemusin II | RRWCFRVCYKGFCYRKCR-NH2 | Atlantic horseshoe crab | Induce necrotic cell death | Cell viability assay | K562 | Human erythroleukemia | EC50 : 22 μM |
| dbacp05597 | Polyphemusin III | RRGCFRVCYRGFCFQRCR | Atlantic horseshoe crab | Induce permeabilization of the cytoplasmic membrane | Trypan blue exclusion assay and Lactate dehydrogenase(LDH)-release assay | HL-60 | Human cervical cancer | IC50 : < 10 μM |
| dbacp06192 | Tachyplesin I | KWCFRVCYRGICYRRCR | Hemocytes, Southeast Asia, Japanese horseshoe crab | Apoptosis inducing | Luciferase reporter assay, TUNEL assay | T167 | Squamous cell oral carcinoma | Not found |
| dbacp06193 | Tachyplesin I | KWCFRVCYRGICYRRCR | Hemocytes, Southeast Asia, Japanese horseshoe crab | Apoptosis inducing | Luciferase reporter assay, TUNEL assay | T-409 | Squamous cell oral carcinoma | Not found |
| dbacp06194 | Tachyplesin I (Tac; TP1; Horseshoe Crab, arachnids, Chelicerata, arthropods, invertebrates, animals) | KWCFRVCYRGICYRRCR | Japanese horseshoe crab | Not specified | Not specified | Not found | Not found | Not found |
| dbacp07466 | Tachyplesin | KWCFRVCYRGICYIRRCR | Horseshoe crab | Fas activation drives apoptosis/necroptosis | MTT assay | A-549 | Lung Cancer | IC50 = 35 µg/ml |
| dbacp07467 | Tachyplesin | KWCFRVCYRGICYIRRCR | Horseshoe crab | Fas activation drives apoptosis/necroptosis | MTT assay | H-460 | Lung Cancer | IC50 = 25 µg/ml |