38 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp01142 | Amphipathic peptide CT1 | MKTQFVILIVAVVLLQLISHSEAFLGALWNVAKSVFGKRGLRNFDDLDDTFEPEMSEADLKYLQDLLR | Scorpions, Morelos, located in South-Central Mexico (Mexican scorpion) | Not specified | MTT/MTS assay | MCF-7 | Breast cancer | IC50 : 6.3-12.5 μM |
| dbacp01143 | Amphipathic peptide VmCT1 | MKTQFVILIVAVVLLQLISHSEAFLGALWNVAKSVFGKRGLRNFDDLDDTFEPEMSEADLKYLQDLLR | Scorpions, Morelos, located in South-Central Mexico (Mexican scorpion) | Not specified | Not specified | Not found | Not found | Not found |
| dbacp01846 | BMAP-27 | GRFKRFRKKFKKLFKKLSPVIPLLHLG | Cattle | Cell membrane disintegration | Not specified | Not found | Not found | Not found |
| dbacp01847 | BMAP-27 | GRFKRFRKKFKKLFKKLSPVIPLLHLG | Cattle | Cell membrane disintegration | Not specified | Not found | Not found | Not found |
| dbacp01848 | BMAP-28 | GGLRSLGRKILRAWKKYGPIIVPIIRIG | Cattle | Cell membrane disintegration | Not specified | Not found | Not found | Not found |
| dbacp01849 | BMAP-28 | GGLRSLGRKILRAWKKYGPIIVPIIRIG | Peripheral neutrophils; Cattle | Cell membrane disintegration | Not specified | Not found | Not found | Not found |
| dbacp02309 | Catfish PACAP38 | HSDGIFTDSYSRYRKQMAVKKYLAAVLGRRYRQRFRNK | Sharptooth catfish, North Africa | Cell membrane penetration | In vitro cell proliferation assay | H460 | Lung cancer | IC50 :13.17 μM |
| dbacp03056 | GF-17 | GFKRIVQRIKDFLRNLV | Derivative of LL-37; nMR-based discovery; Sequence truncation | Rupture cancer cell membranes | Not specified | Not found | Not found | Not found |
| dbacp03382 | Indolicidin | ILPWKWPWWPWRR | Cattle neutrophils | Not specified | Not specified | Not found | Not found | Not found |
| dbacp03414 | Interferon gamma (IFN-gamma) | MKYTSYFLALLLCGLLGFSGSYGQGQFFREIENLKEYFNASSPDVAKGGPLFSEILKNWKDESDKKIIQSQIVSFYFKLFENLKDNQVIQRSMDIIKQDMFQKFLNGSSEKLEDFKKLIQIPVDDLQIQRKAINELIKVMNDLSPKSNLRKRKRSQNLFRGRRASM | Cattle (Bovine) | Total regulation of immune defense | Not specified | Not found | Not found | Not found |
| dbacp03422 | Interferon gamma (IFN-gamma) | MNYTSFIFAFQLCIILCSSGYYCQAMFFKEIEELKGYFNASNPDVADGGSLFVDILKNWKEESDKTIIQSQIVSFYLKMFENLKDDDQRIQRSMDTIKEDMLDKLLNTSSSKRDDFLKLIQIPVNDLQVQRKAINELFKVMNDLSPRSNLRKRKRSQNLFRGRRASK | Cat | Immunomodulatory activity | Not specified | Not found | Acute leukaemia | Not found |
| dbacp03643 | Lactoferricin B | FKCRRWQWRMKKLGAPSITCVRRAF | Cattle | Disintegration of cell membrane | Not specified | Not found | Not found | MIC : 0.3 - 150 pg/ml |
| dbacp04148 | LL 37 | LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES | Also known human cathelicidin | Plasma membrane perturbations | MTT/MTS assay | MCF-7 | Breast cancer | LC50 : 21 at 100 µM |
| dbacp04149 | LL 37 | LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES | Also known human cathelicidin | Plasma membrane perturbations | MTT/MTS assay | LNCaP | Prostate cancer | LC50 : 27 at 100 µM |
| dbacp04150 | LL 37 | LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES | Also known human cathelicidin | Plasma membrane perturbations | MTT/MTS assay | OVRCAR-3 | Ovarian cancer | LC50 : 24 at 100 µM |
| dbacp04696 | Monocyte chemotactic protein 1B (MCP-1B; Fragment) | DAINSPVTCCYTLTSKKISMQRLMSYRRVTSSKCPKEAVIFKTIAGKEICAEPKXXWVQDSISHLDKKNQXPKP | Cattle (Bovine) | Not specified | Not specified | Not found | Not found | Not found |
| dbacp05012 | Omiganan MBI-226 | ILRWPWWPWRRK | Cattle neutrophils | Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis | MTT/MTS assay | U-937 | Lymphoma cancer | IC50 : 80 - 85 µg/ml |
| dbacp05471 | Peptidoglycan recognition protein 1 | MSRRYTPLAWVLLALLGLGAAQDCGSIVSRGKWGALASKCSQRLRQPVRYVVVSHTAGSVCNTPASCQRQAQNVQYYHVRERGWCDVGYNFLIGEDGLVYEGRGWNTLGAHSGPTWNPIAIGISFMGNYMHRVPPASALRAAQSLLACGAARGYLTPNYEVKGHRDVQQTLSPGDELYKIIQQWPHYRRV | Cattle (Bovine) | Provoking in immune responses | Not specified | Not found | Not found | Not found |
| dbacp05875 | Ranatuerin-2-AW A6W, A10W | GFMKTWKNVWKNVAATLLKLLK | Sequence truncation, Amino acid substitution, animal-derived, natural derivative | Membrane disruption | Not specified | Not found | Not found | Not found |
| dbacp05876 | Ranatuerin-2-AW D4K, D19K, K20L | GFMKTAKNVAKNVAATLLKLLK | Sequence truncation, Amino acid substitution, animal-derived, natural derivative | Membrane disruption | Not specified | Not found | Not found | Not found |
| dbacp06154 | StigA16 | FFKLIPKLVKGLISAF | Amino acid substitution, amino acid truncation, animal-derived, natural derivative | Disruption of cell membrane | MTT assay | 3T3 | Renal cell adenocarcinoma | IC 50 : 13.01 μM |
| dbacp06155 | StigA16 | FFKLIPKLVKGLISAF | Amino acid substitution, amino acid truncation, animal-derived, natural derivative | Disruption of cell membrane | MTT assay | HeLa | Mouse melanoma | IC 50 : 13.01 μM |
| dbacp06156 | StigA16 | FFKLIPKLVKGLISAF | Amino acid substitution, amino acid truncation, animal-derived, natural derivative | Disruption of cell membrane | MTT assay | 786-0 | Human cervix adenocarcinoma | IC 50 : 13.01 μM |
| dbacp06157 | StigA16 | FFKLIPKLVKGLISAF | Amino acid substitution, amino acid truncation, animal-derived, natural derivative | Disruption of cell membrane | MTT assay | B16 | Human pancreas adenocarcinoma | IC 50 : 13.01 μM |
| dbacp06158 | StigA16 | FFKLIPKLVKGLISAF | Amino acid substitution, amino acid truncation, animal-derived, natural derivative | Disruption of cell membrane | MTT assay | Panc | Mouse fibroblast | IC 50 : 13.01 μM |
| dbacp06388 | Turgencin B | GIKEML_CnMACAQTVC_KKSGGPLCDTCQAACKALG-NH2 | Tunicate | Disruption of cell membranes | Human cell viability assay | A2058 | Melanoma cancer | IC50 : 4.1μM |
| dbacp06389 | Turgencin A | GPKTKAACKMACKLATCGKKPGGWKCKLCELGCDAV | Tunicate | Disruption of cell membranes | Human cell viability assay | A2058 | Melanoma cancer | IC50 : 1.4 μM |
| dbacp06390 | Turgencin A | GPKTKAACKMACKLATCGKKPGGWKCKLCELGCDAV-NH2 | Tunicate | Disruption of cell membranes | Human cell viability assay | A2058 | Melanoma cancer | IC50 : 1.4 μM |
| dbacp06391 | Turgencin A | GPKTKAACKMACKLATCGKKPGGWKCKLCELGCDAV | Tunicate | Disruption of cell membranes | Human cell viability assay | A2058 | Melanoma cancer | IC50 : 1.4 μM |
| dbacp06392 | Turgencin B | GIKEMLCnMACAQTVCKKSGGPLCDTCQAACKALG | Tunicate | Disruption of cell membranes | Human cell viability assay | A2059 | Melanoma cancer | IC50 : 4.1 μM |
| dbacp06393 | Turgencin B | GIKEMLCnMACAQTVCKKSGGPLCDTCQAACKALG | Tunicate | Disruption of cell membranes | Human cell viability assay | A2059 | Melanoma cancer | IC50 : 4.1 μM |
| dbacp06531 | VmCT1 | FLGALWNVAKSVF | Scorpions, Morelos, located in South-Central Mexico | Not specified | Not specified | Not found | Not found | Not found |
| dbacp06761 | RP7 | ATRQPNH | RAGE(receptor for advanced glycation end product) inhibitor | Apoptosis inducing | MTT assay | MDA-MB-231 | Breast Cancer | IC50 = 24.5 µM |
| dbacp06762 | RP7 | ATRQPNH | RAGE(receptor for advanced glycation end product) inhibitor | Apoptosis inducing | MTT assay | BT-549 | Breast Cancer | IC50 = 29.9 µM |
| dbacp07391 | Ranatuerin-2 | GLFLDTLKGAAKDVAGKLEGLKCKITGCKLP | Rana catesbeiana | Not Available | MTT assay | A-549 | Lung Cancer | IC50 > 128 µM |
| dbacp07392 | Ranatuerin-2 | GLFLDTLKGAAKDVAGKLEGLKCKITGCKLP | Rana catesbeiana | Not Available | MTT assay | MCF-7 | Breast Cancer | IC50 > 128 µM |
| dbacp07393 | Ranatuerin-2 | GLFLDTLKGAAKDVAGKLEGLKCKITGCKLP | Rana catesbeiana | Not Available | MTT assay | HeLa | Cervical Cancer | IC50 > 128 µM |
| dbacp07394 | Ranatuerin-2 | GLFLDTLKGAAKDVAGKLEGLKCKITGCKLP | Rana catesbeiana | Not Available | MTT assay | LoVo | Colon Cancer | IC50 = 128 µM |