340 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp00005 | Citropin modified peptide-3 | GLFAVIKKVASVIGGL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 6 M |
| dbacp00014 | Citropin modified peptide-5 | GLFDVIKAVASVIGGL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 100 µM |
| dbacp00023 | Citropin modified peptide-7 | GLFDVIKKVAAVIGGL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp00035 | Enkephalins7 analogue-8 | YA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 6.5% inhibition at 10-6 M |
| dbacp00036 | Enkephalins7 analogue-8 | YA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 14% inhibition at 10-5 M |
| dbacp00037 | Enkephalins7 analogue-8 | YA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 7.5% inhibition at 10-4 M |
| dbacp00038 | Enkephalins7 analogue-8 | YA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 14% inhibition at 10-3 M |
| dbacp00061 | Enkephalins7 analogue-9 | YSA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 3.9% inhibition at 10-5 M |
| dbacp00062 | Enkephalins7 analogue-9 | YSA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 7.3% inhibition at 10-3 M |
| dbacp00086 | Enkephalins7 analogue-10 | YSA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 3.0% inhibition at 10-6 M |
| dbacp00087 | Enkephalins7 analogue-10 | YSA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 4.7% inhibition at 10-5 M |
| dbacp00088 | Enkephalins7 analogue-10 | YSA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 2.7% inhibition at 10-4 M |
| dbacp00089 | Enkephalins7 analogue-10 | YSA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 7.3% inhibition at 10-3 M |
| dbacp00102 | Citropin modified peptide-11 | GLFDVIKKVASVIKGL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp00111 | Citropin modified peptide-13 | GLFDVIKKVASVIKKL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp00120 | Citropin modified peptide-14 | GLFDVIAKVASVIKKL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp00133 | Enkephalins7 analogue-15 | YSA*G | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 1.6% inhibition at 10-6 M |
| dbacp00134 | Enkephalins7 analogue-15 | YSA*G | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 2.9% inhibition at 10-5 M |
| dbacp00135 | Enkephalins7 analogue-15 | YSA*G | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 5.9% inhibition at 10-4 M |
| dbacp00136 | Enkephalins7 analogue-15 | YSA*G | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 17.9% inhibition at 10-3 M |
| dbacp00154 | Citropin modified peptide-15 | GLFAVIKKVASVIKGL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp00167 | Enkephalins7 analogue-16 | YRA*G | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 1.2% inhibition at 10-5 M |
| dbacp00168 | Enkephalins7 analogue-16 | YRA*G | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 3.3% inhibition at 10-4 M |
| dbacp00169 | Enkephalins7 analogue-16 | YRA*G | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 19.4% inhibition at 10-3 M |
| dbacp00187 | Citropin modified peptide-16 | GLFAVIKKVASVIKKL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp00200 | Enkephalins7 analogue-17 | YA*GFM | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 0.8% inhibition at 10-6 M |
| dbacp00201 | Enkephalins7 analogue-17 | YA*GFM | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 1.4% inhibition at 10-5 M |
| dbacp00202 | Enkephalins7 analogue-17 | YA*GFM | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 2.4% inhibition at 10-4 M |
| dbacp00203 | Enkephalins7 analogue-17 | YA*GFM | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 18.3% inhibition at 10-3 M |
| dbacp00221 | Citropin modified peptide-17 | GLFAVIKKVAAVIKKL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp00234 | Enkephalins7 analogue-18 | YA*GFM | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 2.4% inhibition at 10-6 M |
| dbacp00235 | Enkephalins7 analogue-18 | YA*GFM | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 4.5% inhibition at 10-5 M |
| dbacp00236 | Enkephalins7 analogue-18 | YA*GFM | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 11.4% inhibition at 10-4 M |
| dbacp00237 | Enkephalins7 analogue-18 | YA*GFM | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 23.2% inhibition at 10-3 M |
| dbacp00256 | Citropin modified peptide-18 | GLFAVIKKVAAVIRRL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp00265 | Citropin modified peptide-19 | GLFAVIKKVAKVIKKL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp00274 | Citropin modified peptide-22 | GLFKVIKKVASVIGGL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp00282 | Enkephalins7 analogue-23 | YGGFMA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 4.1% inhibition at 10-6 M |
| dbacp00283 | Enkephalins7 analogue-23 | YGGFMA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 70.7% inhibition at 10-5 M |
| dbacp00284 | Enkephalins7 analogue-23 | YGGFMA* | Synthetic Peptide | Apoptosis inducing | MTT/MTS assay | HBL | Skin cancer | 34.4% inhibition at 10-3 M |
| dbacp00296 | Citropin modified peptide-23 | GLFKVIKKVAKVIKKL | Amphibian skin secretions | Penetration and disruption of the membrane | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp00774 | A12L | KWKSFLKTFKSLKKTVLHTALKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | A-375 | Skin cancer | IC50 : 4.3 µMo/L |
| dbacp00779 | A12L | KWKSFLKTFKSLKKTVLHTALKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | B-16 | Skin cancer | IC50 : 5.2 µMo/L |
| dbacp00782 | A12L/A20L | KWKSFLKTFKSLKKTVLHTLLKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | A-375 | Skin cancer | IC50 : 8.7 µMo/L |
| dbacp00787 | A12L/A20L | KWKSFLKTFKSLKKTVLHTLLKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | B-16 | Skin cancer | IC50 : 4.4 µMo/L |
| dbacp00790 | A12L/A20L/A23L | KWKSFLKTFKSLKKTVLHTLLKLISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | A-375 | Skin cancer | IC50 : 7.2 µMo/L |
| dbacp00795 | A12L/A20L/A23L | KWKSFLKTFKSLKKTVLHTLLKLISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | B-16 | Skin cancer | IC50 : 4.6 µMo/L |
| dbacp00798 | A20L | KWKSFLKTFKSAKKTVLHTLLKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | A-375 | Skin cancer | IC50 : 6.5 µMo/L |
| dbacp00803 | A20L | KWKSFLKTFKSAKKTVLHTLLKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | B-16 | Skin cancer | IC50 : 7.8 µMo/L |
| dbacp00999 | Alloferon 1 | HGVSGHGQHGVHG | Blow fly | Cell membrane disintegration | Not specified | Not found | Skin cancer | Not found |
| dbacp01256 | Aurein 3.1 | GLFDIVKKIAGHIAGSI | Southern bell frog, Australia | Cell membrane disruption | Not specified | Skin tumor cell line | Skin cancer | LC50 : 10-100 µM |
| dbacp01265 | Aurein 3.1 | GLFDIVKKIAGHIAGSI | Southern bell frog, Australia | Cell membrane disruption | Not specified | Skin tumor cell line | Skin cancer | LC50 : 10-100 µM |
| dbacp01275 | Aurein 3.2 | GLFDIVKKIAGHIASSI | Southern bell frog, Australia | Cell membrane disruption | Not specified | Skin tumor cell line | Skin cancer | LC50 : 10 µM |
| dbacp01285 | Aurein 3.3 | GLFDIVKKIAGHIVSSI | Southern bell frog, Australia | Cell membrane disruption | Not specified | Skin tumor cell line | Skin cancer | LC50 : 10 µM |
| dbacp01315 | Aurein-2.5 | MAFLKKSLFLVLFLGLVSLSICEKEKRQNEEDEDENEAANHEEGSEEKRGLFDIVKKVVGAFGSLGKRNDLE | Green and golden bell frog | Not specified | Not specified | Not found | Skin cancer | Not found |
| dbacp01324 | Aurein-2.5 | GLFDIVKKVVGAFGSL | Green and golden bell frog | Not specified | Not specified | Not found | Skin cancer | Not found |
| dbacp01410 | Aurein1.2 | GLFDIIKKIAESF | Southern bell frog | Cell membrane disruption | Not specified | Skin tumor cell line | Skin cancer | LC50 : 10 µM |
| dbacp01419 | Aurein2.5 | GLFDIVKKVVGAFGSL | Southern bell frog | Cell membrane disruption | Not specified | Skin tumor cell line | Skin cancer | LC50 : 10 µM |
| dbacp01428 | Aurein2.6 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disruption | Not specified | Skin tumor cell line | Skin cancer | LC50 : 10 µM |
| dbacp01533 | BC46 | c[(bA)(bA)RKD] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp01538 | BC48 | c[(bA)GRKD] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp01543 | BC49 | c[(bA)(4aba)RKD] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp01548 | BC50 | c[(4aba)(bA)RKD] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp01553 | BC70 | c[(bA)(k)RKD(1-D-NAl)] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp01558 | BC71 | c[(bA)(k)RKD(2-D-NAl)] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp01563 | BC72 | c[(bA)(o)RKD(f)] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp01568 | BC74 | c[(bA)(k)(Fguan)KD(f)] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp01573 | BC75 | c[(bA)(k)RKD(D-Bip)] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp01578 | BC81 | c[(2233tmpa)(k)RKD(2-D-NAl)] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp01583 | BC83 | c[(bA)(k)RKD(D-2Anth)] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp01588 | BC84 | c[(bA)(k)RKD(w)] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp02018 | Buforin IIb | RAGLQFPVGRLLRRLLRRLLR | Histone H2A | Inducing mitochondria-dependent apoptosis | MTT/MTS assay | LOXIMVI | Skin cancer | IC50 : 9.5 µg/ml |
| dbacp02019 | Buforin IIb | RAGLQFPVGRLLRRLLRRLLR | Histone H2A | Inducing mitochondria-dependent apoptosis | MTT/MTS assay | MALME-3M | Skin cancer | IC50 : 10.9 µg/ml |
| dbacp02020 | Buforin IIb | RAGLQFPVGRLLRRLLRRLLR | Histone H2A | Inducing mitochondria-dependent apoptosis | MTT/MTS assay | M14 | Skin cancer | IC50 : 15.1 µg/ml |
| dbacp02021 | Buforin IIb | RAGLQFPVGRLLRRLLRRLLR | Histone H2A | Inducing mitochondria-dependent apoptosis | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 11.1 µg/ml |
| dbacp02022 | Buforin IIb | RAGLQFPVGRLLRRLLRRLLR | Histone H2A | Inducing mitochondria-dependent apoptosis | MTT/MTS assay | SK-MEL-5 | Skin cancer | IC50 : 8.9 µg/ml |
| dbacp02023 | Buforin IIb | RAGLQFPVGRLLRRLLRRLLR | Histone H2A | Inducing mitochondria-dependent apoptosis | MTT/MTS assay | UACC-257 | Skin cancer | IC50 : 12.5 µg/ml |
| dbacp02024 | Buforin IIb | RAGLQFPVGRLLRRLLRRLLR | Histone H2A | Inducing mitochondria-dependent apoptosis | MTT/MTS assay | UACC-62 | Skin cancer | IC50 : 10.6 µg/ml |
| dbacp02160 | C7A | KILRGVAKKIMRTFLRRISKDILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 :10.6 ± 0.4 µM |
| dbacp02161 | C7A | KILRGVAKKIMRTFLRRISKDILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 :13.0 ± 1.0 µM |
| dbacp02162 | C7A | KILRGVAKKIMRTFLRRISKDILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 :12.1 ± 1.6 µM |
| dbacp02163 | C7A | KILRGVAKKIMRTFLRRISKDILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 :37 ± 4.3 µM |
| dbacp02164 | C7A | KILRGVAKKILRTFLRRISKDILTGKK | NK-2 variants | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 10.6 ± 0.4 µM |
| dbacp02165 | C7A | KILRGVAKKILRTFLRRISKDILTGKK | NK-2 variants | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 13.0 ± 1.0 µM |
| dbacp02166 | C7A | KILRGVAKKILRTFLRRISKDILTGKK | NK-2 variants | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 12.1 ± 1.6 µM |
| dbacp02167 | C7A | KILRGVAKKILRTFLRRISKDILTGKK | NK-2 variants | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 3.7 ± 4.3 µM |
| dbacp02181 | C7A-D21K | KILRGVAKKIMRTFLRRISKKILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 8.4 ± 0.2 µM |
| dbacp02182 | C7A-D21K | KILRGVAKKIMRTFLRRISKKILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 12.3 ± 2.0 µM |
| dbacp02183 | C7A-D21K | KILRGVAKKIMRTFLRRISKKILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 8.3 ± 0.5 µM |
| dbacp02184 | C7A-D21K | KILRGVAKKIMRTFLRRISKKILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 12.3 ± 1.0 µM |
| dbacp02185 | C7A-D21k | KILRGVAKKIMRTFLRRISKKILTGKK | NK-2 variants | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 8.4 ± 0.2 µM |
| dbacp02186 | C7A-D21k | KILRGVAKKIMRTFLRRISKKILTGKK | NK-2 variants | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 12.3 ± 2.0 µM |
| dbacp02187 | C7A-D21k | KILRGVAKKIMRTFLRRISKKILTGKK | NK-2 variants | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 8.3 ± 0.5 µM |
| dbacp02188 | C7A-D21k | KILRGVAKKIMRTFLRRISKKILTGKK | NK-2 variants | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 12.3 ± 1.0 µM |
| dbacp02202 | C7A-Δ | KILRGVAKKIMRTFLRRILTGKK | NK-2 variants | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 7.5 ± 0.4 µM |
| dbacp02203 | C7A-Δ | KILRGVAKKIMRTFLRRILTGKK | NK-2 variants | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 13.8 ± 2.0 µM |
| dbacp02204 | C7A-Δ | KILRGVAKKIMRTFLRRILTGKK | NK-2 variants | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 9.3 ± 1.5 µM |
| dbacp02205 | C7A-Δ | KILRGVAKKIMRTFLRRILTGKK | NK-2 variants | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 13.1 ± 0.9 µM |
| dbacp02206 | C7A-Δ | KILRGVAKKIMRTFLRRILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 13.8 ± 2.0 µM |
| dbacp02207 | C7A-Δ | KILRGVAKKIMRTFLRRILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 9.3 ± 1.5 µM |
| dbacp02208 | C7A-Δ | KILRGVAKKIMRTFLRRILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 13.1 ± 0.9 µM |
| dbacp02222 | C7A-Δ | KILRGVAKKIMRTFLRRILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 7.5 ± 0.4 µM |
| dbacp02270 | Camel | KWKLFKKIGAVLKVL | Ceropin-Melittin hybrid | Cell swelling and rupture of the plasma membrane | MTT/MTS assay | B16-F10 | Skin cancer | LC50 : 1.75 µM |
| dbacp02273 | Camel | KWKLFKKIGAVLKVL | Ceropin-Melittin hybrid | Cell swelling and rupture of the plasma membrane | MTT/MTS assay | WM1158 | Skin cancer | LC50 : 4.1 µM |
| dbacp02338 | Cecropin A | KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAK | Isolated from the giant silk moth, cecropia moth | Membrane damage; Apoptotic cell death; Necrosis | MTT/MTS assay | SCC12 | Skin cancer | IC50 : 1 µM |
| dbacp02339 | Cecropin A | KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAK | Isolated from the giant silk moth, cecropia moth | Membrane damage; Apoptotic cell death; Necrosis | MTT/MTS assay | SCC25 | Skin cancer | IC50 : 2.2 µM |
| dbacp02340 | Cecropin A | KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAK | Isolated from the giant silk moth, cecropia moth | Membrane damage; Apoptotic cell death; Necrosis | Cell viability assay | SCC25 | Skin cancer | 0.6 ± 0.6% cell growth inhibition at 10 µM |
| dbacp02341 | Cecropin A | KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAK | Isolated from the giant silk moth, cecropia moth | Membrane damage; Apoptotic cell death; Necrosis | Cell viability assay | SCC25 | Skin cancer | 107.0 ± 5.0% cell growth inhibition at 1 µM |
| dbacp02492 | Citropin 1.1 | GLFDVIKKVASVIGGL | Amphibian skin secretions | Penetration and disruption of the membranes | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp02503 | Citropin 1.1D | glfdvikkvasviggl | Amphibian skin secretions | Penetration and disruption of the membranes | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp02550 | CPF-ST3 | GLLGPLLKIAAKVGSNLL | Diploid clawed frog, Western clawed frog,Africa | Cell membrane disintegration | Not specified | Not found | Skin cancer | Not found |
| dbacp02551 | CPF-ST3 | GLLGPLLKIAAKVGSNLL | Diploid clawed frog, Western clawed frog,Africa | Cell membrane disintegration | Not specified | Not found | Skin cancer | Not found |
| dbacp02933 | Figainin 1 | MAFLKKSLFLVLFLGLVSLSIGEEEKREEEEKNEEGANQEENAENKEKRFIGTLIPLALGALTKLFKG | Chaco tree frog | Anti-proliferative action | MTT/MTS assay | NIH/3T3 | Skin cancer | IC50 : 13 µM |
| dbacp02936 | Figainin 1 | MAFLKKSLFLVLFLGLVSLSIGEEEKREEEEKNEEGANQEENAENKEKRFIGTLIPLALGALTKLFKG | Chaco tree frog | Anti-proliferative action | MTT/MTS assay | B16F10 | Skin cancer | IC50 : 10.5 µM |
| dbacp02939 | Figainin 1 | MAFLKKSLFLVLFLGLVSLSIGEEEKREEEEKNEEGANQEENAENKEKRFIGTLIPLALGALTKLFKG | Chaco tree frog | Anti-proliferative action | MTT/MTS assay | MCF | Skin cancer | IC50 : 13.7 µM |
| dbacp02942 | Figainin 1 | MAFLKKSLFLVLFLGLVSLSIGEEEKREEEEKNEEGANQEENAENKEKRFIGTLIPLALGALTKLFKG | Chaco tree frog | Anti-proliferative action | MTT/MTS assay | HeLa | Skin cancer | IC50 : 11.1 µM |
| dbacp02951 | Figainin 2 | MAFLKKSLFLVLFLGIVSLSVCEEEKREGEEKEEKREEEEGKEENEDGNEEHKEKRFLGAILKIGHALAKTVLPMVTNAFKPKQ | Chaco tree frog | Necrosis; Apoptosis | MTT/MTS assay | B16F10 | Skin cancer | IC50 : 12.8 µM |
| dbacp02953 | Figainin 2 | MAFLKKSLFLVLFLGIVSLSVCEEEKREGEEKEEKREEEEGKEENEDGNEEHKEKRFLGAILKIGHALAKTVLPMVTNAFKPKQ | Chaco tree frog | Necrosis; Apoptosis | MTT/MTS assay | MCF-7 | Skin cancer | IC50 : 15.3 µM |
| dbacp02977 | GA-K3 | FLGWLFKWAKK | Undecapeptide analogues derived from Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 27.39 µM |
| dbacp02984 | GA-K3 | FLGWLFKWAKK | Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 27.39 µM |
| dbacp02991 | GA-K4 | FLKWLFKWAKK | Undecapeptide analogues derived from Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 :22.25 µM |
| dbacp02998 | GA-K4 | FLKWLFKWAKK | Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 22.25 µM |
| dbacp03005 | GA-W3 | FLGWLFKWAWK | Undecapeptide analogues derived from Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 13.97 µM |
| dbacp03012 | GA-W3 | FLGWLFKWAWK | Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 13.97 µM |
| dbacp03019 | GA-W4 | FLWWLFKWAWK | Undecapeptide analogues derived from Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 13.16 µM |
| dbacp03026 | GA-W4 | FLWWLFKWAWK | Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 13.16 µM |
| dbacp03159 | GR01 | c[CRKDC]Disulfidebridge | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp03164 | GR16 | c[KRKDF] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp03169 | GR35 | c[KRAAF] | AMOP domain of ISM trigger apoptosis | Inducing apoptosis | LDH assay | HUVECs | Skin cancer | Not found |
| dbacp03529 | KW5 | KAAKKAAKAAKKAAKAAKKAA | Bovine lactoferrin (Lf-B) | Through interactions with the plasma membrane | MTT/MTS assay | FEMX | Skin cancer | IC50 : 30 ± 3 µM |
| dbacp03549 | L1 | PEWFKCRRWQWRMKKLGA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : > 404 µM |
| dbacp03552 | L10 | PAARKAFRWAWRMLKKAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 24 µM |
| dbacp03555 | L11 | PAARKAARWAWRMLKKGA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 116 µM |
| dbacp03558 | L12 | PAWRKAFRWAKRMLKKAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 7.9 µM |
| dbacp03561 | L13 | PAWRKAFRKAWRMLKKAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 14 µM |
| dbacp03564 | L14 | PAWRKARRWAWRMKKLAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 125 µM |
| dbacp03567 | L15 | PAWRKARRWARRMKKLAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 87 µM |
| dbacp03571 | L17A | KWKSFLKTFKSAKKTVAHTALKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | A-375 | Skin cancer | IC50 : > 83.6 µMo/L |
| dbacp03576 | L17A | KWKSFLKTFKSAKKTVAHTALKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | B-16 | Skin cancer | IC50 : > 83.6 µMo/L |
| dbacp03579 | L17A/L21A | KWKSFLKTFKSAKKTVAHTAAKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | A-375 | Skin cancer | IC50 : > 83.6 µMo/L |
| dbacp03584 | L17A/L21A | KWKSFLKTFKSAKKTVAHTAAKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | B-16 | Skin cancer | IC50 : >83.6 µMo/L |
| dbacp03586 | L2 | PAWFKARRWAWRMKKLAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 144 µM |
| dbacp03590 | L21A | KWKSFLKTFKSAKKTVAHTAAKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | A-375 | Skin cancer | IC50 : 59.8 µMo/L |
| dbacp03595 | L21A | KWKSFLKTFKSAKKTVAHTAAKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | B-16 | Skin cancer | IC50 : 63.5 µMo/L |
| dbacp03597 | L3 | PAWRKAFRWAWRMKKLAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 32 µM |
| dbacp03600 | l3,10,13K7,8K4R2L9 | KLlRLLkkLlRLlLK | Diastereomeric peptide | Plasma membrane perturbation; Necrosis | XTT assay | B16-F10 | Skin cancer | LC50 : 2.5 µM |
| dbacp03602 | l3,4,8,10K5L7 | KlllKLKlKlLK | Diastereomeric peptide | Plasma membrane perturbation; Necrosis | XTT assay | B16-F10 | Skin cancer | LC50 : 100 µM |
| dbacp03604 | L4 | PAWFKARRWAWRMLKKAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 31 µM |
| dbacp03607 | L5 | PAWRKAFRWAWRMLKKAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 6.6 µM |
| dbacp03610 | L6 | PAWRKAFRWAARMLKKAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 11 µM |
| dbacp03614 | L6A | KWKSFAKTFKSAKKTVLHTALKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | A-375 | Skin cancer | IC50 : 58.7 µMo/L |
| dbacp03619 | L6A | KWKSFAKTFKSAKKTVLHTALKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | B-16 | Skin cancer | IC50 : 62.5 µMo/L |
| dbacp03622 | L6A/L17A | KWKSFAKTFKSAKKTVAHTALKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | A-375 | Skin cancer | IC50 : >83.6 µMo/L |
| dbacp03627 | L6A/L17A | KWKSFAKTFKSAKKTVAHTALKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | B-16 | Skin cancer | IC50 : >83.6 µMo/L |
| dbacp03629 | L7 | PAWRKAFRAAWRMLKKAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 16 µM |
| dbacp03632 | L8 | PAWAKAFRAAARMKLKAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 110 µM |
| dbacp03635 | L9 | PAWRKAARWAWRMLKKAA | Lactoferrin | Cell membrane disintegration | MTT/MTS assay | Meth A | Skin cancer | IC50 : 35 µM |
| dbacp03733 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | FEMX | Skin cancer | IC50 : 40 ± 7 µM |
| dbacp03735 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | KMS-5 | Skin cancer | IC50 : 38 µM |
| dbacp03737 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | KMM-1 | Skin cancer | IC50 : 57 µM |
| dbacp03738 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | Sudhl-4 | Skin cancer | IC50 : 16 µM |
| dbacp04302 | LTX-315 | KKWWKKW-Dip-K | Synthetic peptide | Necrosis | MTT/MTS assay | B16F1 | Skin cancer | IC50 : 13.3 µM |
| dbacp04303 | LTX-315 | KKWWKKW-Dip-K | Synthetic peptide | Necrosis | MTT/MTS assay | A375 | Skin cancer | IC50 : 12.7 µM |
| dbacp04304 | LTX-315 | KKWWKKW-Dip-K | Synthetic peptide | Necrosis | MTT/MTS assay | Fem-X | Skin cancer | IC50 : 15.3 µM |
| dbacp04308 | LTX-328 | KAQ-Dip-QKQAW | Synthetic peptide | Necrosis | MTT/MTS assay | Fem-X | Skin cancer | IC50 : >350 µM |
| dbacp04442 | Maculatin 1.3 | GLLGLLGSVVSHVVPAIVGHF | Blue-thighed frog, Australia | Cell membrane disruption | Not specified | Not found | Skin cancer | Not found |
| dbacp04453 | Maculatin 1.4 | GLLGLLGSVVSHVLPAITQHL | Blue-thighed frog, Australia | Cell membrane disruption | Not specified | Not found | Skin cancer | Not found |
| dbacp04631 | MCL-1, BH3 (208-228) | KALETLRRVGDGVQRNHETAF | Anti apoptotic (MCL-1, BFL1) | Inducing apoptosis | Not specified | Not found | Skin cancer | Not found |
| dbacp04643 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 :3.2 ± 0.1 µM |
| dbacp04644 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 :2.1 ± 0.1 µM |
| dbacp04645 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 :1.8 ± 0.1 µM |
| dbacp04646 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 :1.4 ± 0.1 µM |
| dbacp04647 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Natural component of bee venom | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 1.4 ± 0.1 µM |
| dbacp04648 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Natural component of bee venom | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 3.2 ± 0.1 µM |
| dbacp04649 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Natural component of bee venom | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 2.1 ± 0.1 µM |
| dbacp04650 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Natural component of bee venom | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 1.8 ± 0.1 µM |
| dbacp04651 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Natural component of bee venom | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 1.4 ± 0.1 µM |
| dbacp04652 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Main component of honey bee venom | Membrane damage; Apoptotic cell death; Necrosis | Cell viability assay | SCC25 | Skin cancer | 102.9 ± 4.1% cell growth inhibition at 1 µM |
| dbacp04701 | mPep1 | RKAFRWAWRMLKKAAPSITCVR | Bovine lactoferrin (Lf-B) | Necrotic cell death by destroying cellular membrane structure; Apoptotic cell death | MTT/MTS assay | HL-60 | Skin cancer | IC50 :8 µM |
| dbacp04851 | NK-11 | KISKRILTGKK | NK2 derived iNot foundctive control peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : > 100 µM |
| dbacp04852 | NK-11 | KISKRILTGKK | NK2 derived iNot foundctive control peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : > 100 µM |
| dbacp04853 | NK-11 | KISKRILTGKK | NK2 derived iNot foundctive control peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : > 100 µM |
| dbacp04854 | NK-11 | KISKRILTGKK | NK2 derived iNot foundctive control peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : > 100 µM |
| dbacp04855 | NK-2 | KILRGVCKKIMRTFLRRISKDILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 70 µM |
| dbacp04856 | NK-2 | KILRGVCKKIMRTFLRRISKDILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 50 µM |
| dbacp04857 | NK-2 | KILRGVCKKIMRTFLRRISKDILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 50 µM |
| dbacp04858 | NK-2 | KILRGVCKKIMRTFLRRISKDILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 40 µM |
| dbacp04859 | NK-2 | KILRGVCKKIMRTFLRRISKDILTGKK | Residue of 39-65 of porcine NK-lysine | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 4.3±0.3 µM |
| dbacp04860 | NK-2 | KILRGVCKKIMRTFLRRISKDILTGKK | Residue of 39-65 of porcine NK-lysine | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 70 µM (approx.) |
| dbacp04861 | NK-2 | KILRGVCKKIMRTFLRRISKDILTGKK | Residue of 39-65 of porcine NK-lysine | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 50 µM (approx.) |
| dbacp04862 | NK-2 | KILRGVCKKIMRTFLRRISKDILTGKK | Residue of 39-65 of porcine NK-lysine | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 50 µM (approx.) |
| dbacp04863 | NK-2 | KILRGVCKKIMRTFLRRISKDILTGKK | Residue of 39-65 of porcine NK-lysine | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 40 µM (approx.) |
| dbacp04880 | NK11 | KISKRILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : >100 µM |
| dbacp04881 | NK11 | KISKRILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : >100 µM |
| dbacp04882 | NK11 | KISKRILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : >100 µM |
| dbacp04883 | NK11 | KISKRILTGKK | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : >100 µM |
| dbacp05022 | Peptide P | KWKSFLKTFKSAKKTVLHTALKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | A-375 | Skin cancer | IC50 : 17.8 µMo/L |
| dbacp05027 | Peptide P | KWKSFLKTFKSAKKTVLHTALKAISS | PeptideV13K | Membrane disruption mechanism | MTT/MTS assay | B-16 | Skin cancer | IC50 : 11.5 µMo/L |
| dbacp05038 | P18 | KWKLFKKIPKFLHLAKKF | Bovine lactoferrin (Lf-B) | Necrosis; Cell membrane rupture | MTT/MTS assay | M14 | Skin cancer | 92.2 ± 1.02% cell viability at 10 µM |
| dbacp05039 | P18 | KWKLFKKIPKFLHLAKKF | Synthetic peptide | Necrosis; Cell membrane rupture | MTT/MTS assay | M14 | Skin cancer | 71.1 ± 2.84% cell viability at 20 µM |
| dbacp05040 | P18 | KWKLFKKIPKFLHLAKKF | Synthetic peptide | Necrosis; Cell membrane rupture | MTT/MTS assay | M14 | Skin cancer | 50 ± 3.09% cell viability at 40 µM |
| dbacp05041 | P18 | KWKLFKKIPKFLHLAKKF | Synthetic peptide | Necrosis; Cell membrane rupture | MTT/MTS assay | M14 | Skin cancer | 31.5 ± 1.49% cell viability at 60 µM |
| dbacp05042 | P18 | KWKLFKKIPKFLHLAKKF | Synthetic peptide | Necrosis; Cell membrane rupture | MTT/MTS assay | M14 | Skin cancer | 13.8 ± 1.44% cell viability at 80 µM |
| dbacp05043 | P18 | KWKLFKKIPKFLHLAKKF | Synthetic peptide | Necrosis; Cell membrane rupture | MTT/MTS assay | A-375 | Skin cancer | 86 ± 0.57% cell viability at 10 µM |
| dbacp05044 | P18 | KWKLFKKIPKFLHLAKKF | Synthetic peptide | Necrosis; Cell membrane rupture | MTT/MTS assay | A-375 | Skin cancer | 63.8 ± 0.8% cell viability at 20 µM |
| dbacp05045 | P18 | KWKLFKKIPKFLHLAKKF | Synthetic peptide | Necrosis; Cell membrane rupture | MTT/MTS assay | A-375 | Skin cancer | 47.5 ± 1.66% cell viability at 40 µM |
| dbacp05046 | P18 | KWKLFKKIPKFLHLAKKF | Synthetic peptide | Necrosis; Cell membrane rupture | MTT/MTS assay | A-375 | Skin cancer | 26.9 ± 0.5% cell viability at 60 µM |
| dbacp05047 | P18 | KWKLFKKIPKFLHLAKKF | Synthetic peptide | Necrosis; Cell membrane rupture | MTT/MTS assay | A-375 | Skin cancer | 6.5 ± 1.07% cell viability at 80 µM |
| dbacp05094 | P7 | PLLQATLGGGS | Not found | Apoptosis inducing | WST-1 assay | B16-F10 | Skin cancer | IC50 : 1 µM |
| dbacp05441 | Peptide-20 | CSSRTMHHC | Synthetic Peptide | Inducing apoptosis | MTT/MTS assay | B16F10-Nex 2 | Skin cancer | At 100 µM 50% viablity |
| dbacp05442 | Peptide-20 | CSSRTMHHC | Synthetic Peptide | Inducing apoptosis | MTT/MTS assay | A-2058 | Skin cancer | At100 µM 30% viablity |
| dbacp05443 | Peptide-20 | CSSRTMHHC | Synthetic Peptide | Inducing apoptosis | MTT/MTS assay | Skmel-25 | Skin cancer | At 100 µM 55 - 60% viablity |
| dbacp05444 | Peptide-20 | CSSRTMHHC | Synthetic Peptide | Inducing apoptosis | MTT/MTS assay | Skmel-28 | Skin cancer | At 100 µM 35 - 40% viablity |
| dbacp05938 | Retro | LGGIVSAVKKIVDFLG | Amphibian skin secretions | Penetration and disruption of the membranes | Sulforhodamine B assay | Skin tumor cell line | Skin cancer | IC50 : 5 M |
| dbacp06404 | Tyroserleutide | YSL | Synthetic Peptide | Necrosis; Immune regulation | MTT/MTS assay | B16-F10 | Skin cancer | 49.4% Cytotoxic at 0.1 µg/ml |
| dbacp06405 | Tyroserleutide | YSL | Synthetic Peptide | Necrosis; Immune regulation | MTT/MTS assay | B16-F10 | Skin cancer | 51.2% Cytotoxic at 1 µg/ml |
| dbacp06406 | Tyroserleutide | YSL | Synthetic Peptide | Necrosis; Immune regulation | MTT/MTS assay | B16-F10 | Skin cancer | 53.0% Cytotoxic at 10 µg/ml |
| dbacp06407 | Tyroserleutide | YSL | Synthetic Peptide | Necrosis; Immune regulation | MTT/MTS assay | B16-F10 | Skin cancer | 61.2% Cytotoxic at 100 µg/ml |
| dbacp06496 | Vibi G | GTFPCGESCVFIPCLTSAIGCSCKSKVCYKN | Alpine violet, Viola biflora | Cell membrane disintegration | Not specified | Not found | Skin cancer | Not found |
| dbacp06548 | Z1 | KAAKKWAKAAKKAAKAWKKAA | Synthetic | Disruption of cell membrane | MTT/MTS assay | Meth A | Skin cancer | EC50 : > 211 µM |
| dbacp06551 | Z10 | AAKKWAKAKWAKAKKWAKAA | Synthetic | Disruption of cell membrane | MTT/MTS assay | Meth A | Skin cancer | EC50 : > 211 µM |
| dbacp06554 | Z2 | KAAKKWAKAWKKAAKAWKKAA | Synthetic | Disruption of cell membrane | MTT/MTS assay | Meth A | Skin cancer | EC50 : > 211 µM |
| dbacp06567 | Z3 | KAAKKAWKAWKKAAKAAWKKAA | Synthetic | Disruption of cell membrane | MTT/MTS assay | Meth A | Skin cancer | EC50 : >211 µM |
| dbacp06570 | Z4 | KAAKKAWKAAKKAAKWWKKAA | Synthetic | Disruption of cell membrane | MTT/MTS assay | Meth A | Skin cancer | EC50 : 155 µM |
| dbacp06583 | Z5 | KAAKKAWKWAKKAAKWAKKAA | Synthetic | Disruption of cell membrane | MTT/MTS assay | Meth A | Skin cancer | EC50 : 42 µM |
| dbacp06586 | Z6 | KWWKKAAKAAKKAAKAAKKWA | Synthetic | Disruption of cell membrane | MTT/MTS assay | Meth A | Skin cancer | EC50 : 17 µM |
| dbacp06589 | Z7 | KAAKKAWKAAKKAWKAAKKAA | Synthetic | Disruption of cell membrane | MTT/MTS assay | Meth A | Skin cancer | EC50 : 15 µM |
| dbacp06592 | Z8 | AWKKWAKAWKWAKAKWWAKAA | Synthetic | Disruption of cell membrane | MTT/MTS assay | Meth A | Skin cancer | EC50 : 19 µM |
| dbacp06595 | Z9 | AAWKWAWAKKWAKAKKWAKAA | Synthetic | Disruption of cell membrane | MTT/MTS assay | Meth A | Skin cancer | EC50 : 9 µM |
| dbacp06735 | NKL-WT | KLKSKLMVVCNKIGLLKSLCRKFVKSH | Trematomus bernacchii | Apoptosis inducing | luciferase-based ATPlite assay | B16-F10 | Skin Cancer | ATP level = 0.753 ± 0.254 at 40 μM |
| dbacp06736 | NKL-MUT | KLKSKLMVVANKIGLLKSLARKFVKSH | Trematomus bernacchii | Apoptosis inducing | luciferase-based ATPlite assay | B16-F10 | Skin Cancer | ATP level = 0.023 ± 0.007 at 40 μM |
| dbacp06802 | A11 | EYVQTVKSSKG | Annexin A1 | Targeting PD-L3 | Biotin Pull Down assay | A-375 | Skin Cancer | Not Available |
| dbacp06804 | [C/U, G1K, L5Y, K8R]cGm | KURRYUYRQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 2.3 ± 0.2 μM |
| dbacp06810 | [G1K, L5Y, K8R]cGm | KCRRYCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 2.0 ± 0.1 μM |
| dbacp06816 | [D-P L-P]cGm | GCRRLCYKQRCVTYCRGpPR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 3.0 ± 0.1 μM |
| dbacp06820 | [C/U]cGm | GURRLUYKQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 4.6 ± 0.2 μM |
| dbacp06826 | [G1K, K8R]cGm | KCRRLCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 1.7 ± 0.1 μM |
| dbacp06832 | [R4A, R18A]cGm | GCRALCYKQRCVTYCRGA | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 10.3 ± 1.1 μM |
| dbacp06838 | [Y7W, K8R, Y14W]cGm | GCRRLCWRQRCVTWCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 5.4 ± 0.3 μM |
| dbacp06975 | C16-E4Y | EEEEY | Synthetic | Inhibition of cell signalling | WST-8 assay | A-431 | Skin Cancer | 10 % cell viability at 0.05 wt % |
| dbacp07008 | ST101 | vaeareelerlearlgqargelkkwkmrrnqfwlklqr | Synthetic | Prevents C/EBPβ dimerization, induces degradation | Annexin V/ PI staining assay | A-375 | Skin Cancer | mean EC50 value of 2.1 ± 0.4 μmol/L |
| dbacp07014 | Sansalvimide A | LXVLF | Fusarium sp. | Not Available | Not Available | SK-MEL-2 | Skin Cancer | IC50 = 5.9 µg/ml |
| dbacp07029 | [G10a]-SHa | FLSGIVGMLaKLF | Analog of temporin SHa | Dendrimerization enhances stability, selectivity, anticancer efficacy | Resazurin dye assay | MNT-1 | Skin Cancer | IC50 = 15.25 ± 0.80 µM |
| dbacp07036 | [G10a]2-SHa | FLSGIVGMLaKLFKFLKaLMFLSGIVG | Analog of temporin SHa | Dendrimerization enhances stability, selectivity, anticancer efficacy | Resazurin dye assay | MNT-1 | Skin Cancer | IC50 = 4.72 ± 0.36 µM |
| dbacp07043 | [G10a]3-SHa | FLSGIVGMLaKLFFLSGIVGMLaKLFFLSGIVGMLaKLFKK | Analog of temporin SHa | Dendrimerization enhances stability, selectivity, anticancer efficacy | Resazurin dye assay | MNT-1 | Skin Cancer | IC50 = 2.24 ± 0.05 µM |
| dbacp07049 | Jeff-[G10a]2-SHa | FLSGIVGMLaKLF-jeff-FLSGIVGMLaKLF | Analog of temporin SHa | Dendrimerization enhances stability, selectivity, anticancer efficacy | Resazurin dye assay | MNT-1 | Skin Cancer | IC50 = 57.03 ± 6.09 µM |
| dbacp07239 | RB4 | MADSERLSAPGCWAACTNFSRTRK | Derived from protein PLP2 | F-actin modulation induces necrotic death. | MTT assay | B16-F10-Nex 2 | Skin Cancer | EC50 = 0.263 ± 0.585 mol/L × 10-3 |
| dbacp07242 | RB4 | MADSERLSAPGCWAACTNFSRTRK | Derived from protein PLP2 | F-actin modulation induces necrotic death. | MTT assay | A-2058 | Skin Cancer | EC50 = 0.744 ± 0.208 mol/L × 10-3 |
| dbacp07322 | PCC-1 | KKRKKKAFALKFVVDLI | Poecilocoris lewisi | Sp1 suppression, apoptosis, cell-cycle arrest | MTS assay | SK-Mel-28 | Skin Cancer | IC50 = 50.8 µM |
| dbacp07323 | PCC-1 | KKRKKKAFALKFVVDLI | Poecilocoris lewisi | Sp1 suppression, apoptosis, cell-cycle arrest | MTS assay | G361 | Skin Cancer | IC50 = 57.8 µM |
| dbacp07360 | N-Ter-TAT | RDVFTKGYGFGL-GRK(Dansylglycine)KRRQRRRPQ | Synthetic | Mitochondrial targeting, VDAC1-HKII dissociation | MTT assay | A-375 | Skin Cancer | IC50 > 50.0 μM |
| dbacp07361 | Pal-N-Ter-TAT | Pal-RDVFTKGYGFGL-GRK(Dansylglycine)KRRQRRRPQ | Analogue of N-terminal fragment of the VDAC1 protein | Mitochondrial targeting, VDAC1-HKII dissociation | MTT assay | A-375 | Skin Cancer | IC50 = 36.67(Supplementary material)/15.2 ± 0.7 μM(Published paper) |
| dbacp07364 | pFL-N-Ter-TAT | FPWWWPFL-RDVFTKGYGFGL-GRK(Dansylglycine)KRRQRRRPQ | Analogue of N-terminal fragment of the VDAC1 protein | Mitochondrial targeting, VDAC1-HKII dissociation | MTT assay | A-375 | Skin Cancer | IC50 = 11.1 ± 0.1 μM |
| dbacp07465 | ΔM4 | NFFKRIRRAWKRIWKWIYSA | Synthetic | Membrane disruption triggers mitochondrial apoptosis | Not Available | A-375 | Skin Cancer | IC50 = 9.31 μM |
| dbacp07468 | Protonectin | ILGTILGLLKGL | Parachartergus fraternus | Cell penetration without toxic accumulation | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 14.8 ± 0.9 µM |
| dbacp07470 | Protonectin-F | IFGTILGFLKGL | Protonoectin | Cell penetration without toxic accumulation | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 16.0 ± 1.2 µM |
| dbacp07493 | Figainin 1 | FIGTLIPLALGALTKLFK | Boana raniceps | Membrane disruption, α-helix mediated | MTT assay | B16-F10 | Skin Cancer | IC50 = 10.5 µM |
| dbacp07578 | R-DIM-P-LF11 | FQWQRNIRKVRPRVKRINRQWQF | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | A-375 | Skin Cancer | LC50 = 125.0 ± 16.8 μM |
| dbacp07579 | R-DIM-P-LF11 | FQWQRNIRKVRPRVKRINRQWQF | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | SBcl2 | Skin Cancer | LC50 = 10.7 ± 0.2 μM |
| dbacp07580 | R-DIM-P-LF11 | FQWQRNIRKVRPRVKRINRQWQF | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | WM164 | Skin Cancer | LC50 = 20.9 ± 3.9 μM |
| dbacp07581 | R-DIM-P-LF11-322 | PFWRIRIRRPRRIRIRWFP | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | A-375 | Skin Cancer | LC50 = 4.2 ± 0.2 μM |
| dbacp07582 | R-DIM-P-LF11-322 | PFWRIRIRRPRRIRIRWFP | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | SBcl2 | Skin Cancer | LC50 = 2.5 ± 0.1 μM |
| dbacp07583 | R-DIM-P-LF11-322 | PFWRIRIRRPRRIRIRWFP | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | WM164 | Skin Cancer | LC50 = 4.7 ± 0.2 μM |
| dbacp07584 | DIM-LF11-322 | PFWRIRIRRPFWRIRIRR | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | A-375 | Skin Cancer | LC50 = 6.3 ± 0.3 μM |
| dbacp07585 | DIM-LF11-322 | PFWRIRIRRPFWRIRIRR | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | SBcl2 | Skin Cancer | LC50 < 1 ± 0.0 μM |
| dbacp07586 | DIM-LF11-322 | PFWRIRIRRPFWRIRIRR | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | WM164 | Skin Cancer | LC50 = 4.6 ± 0.1 μM |
| dbacp07587 | R-DIM-P-LF11-215 | FWRIRIRRPRRIRIRWF | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | A-375 | Skin Cancer | LC50 = 2.7 ± 0.9 μM |
| dbacp07588 | R-DIM-P-LF11-215 | FWRIRIRRPRRIRIRWF | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | SBcl2 | Skin Cancer | LC50 < 1 ± 0.0 μM |
| dbacp07589 | R-DIM-P-LF11-215 | FWRIRIRRPRRIRIRWF | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | WM164 | Skin Cancer | LC50 = 4.6 ± 0.1 μM |
| dbacp07590 | R-DIM-P-LF11-334 | PWRIRIRRPRRIRIWP | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | A-375 | Skin Cancer | LC50 = 6.6 ± 0.3 μM |
| dbacp07591 | R-DIM-P-LF11-334 | PWRIRIRRPRRIRIWP | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | SBcl2 | Skin Cancer | LC50 = 3.4 ± 0.4 μM |
| dbacp07592 | R-DIM-P-LF11-334 | PWRIRIRRPRRIRIWP | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | WM164 | Skin Cancer | LC50 = 5.0 ± 0.1 μM |
| dbacp07593 | R-DIM-LF11-334-LF11-334 | PWRIRIRRRRIRIRWPPWRIRIRR | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | A-375 | Skin Cancer | LC50 < 1 ± 0.1 μM |
| dbacp07594 | R-DIM-LF11-334-LF11-334 | PWRIRIRRRRIRIRWPPWRIRIRR | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | SBcl2 | Skin Cancer | LC50 < 1 ± 0.1 μM |
| dbacp07595 | R-DIM-LF11-334-LF11-334 | PWRIRIRRRRIRIRWPPWRIRIRR | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | WM164 | Skin Cancer | LC50 = 3.6 ± 0.7 μM |
| dbacp07596 | DIM-LF11-339 | RRWFWRRRRWFWRR | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | A-375 | Skin Cancer | LC50 = 4.8 ± 0.4 μM |
| dbacp07597 | DIM-LF11-339 | RRWFWRRRRWFWRR | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | SBcl2 | Skin Cancer | LC50 = 4.7 ± 0.3 μM |
| dbacp07598 | DIM-LF11-339 | RRWFWRRRRWFWRR | Synthetic | Peptides target phosphatidylserine, trigger apoptosis | MTS assay | WM164 | Skin Cancer | LC50 = 3.8 ± 0.3 μM |
| dbacp07648 | AP1-Z1 | FLFSLIPHAISGLISAFK | AcrAP1 from the venom of the Arabian scorpion | Charge–hydrophobicity balance drives apoptosis | MTT assay | A-375 | Skin Cancer | IC50 = 9.478 μM |
| dbacp07651 | AP1-Z5a | FLFKLIPKAIKGLIKAFK | Mutant of APR-Z1 | Charge–hydrophobicity balance drives apoptosis | MTT assay | A-375 | Skin Cancer | Graph Figure 2B |
| dbacp07654 | AP1-Z5b | FLFKLIKHAIKGLIKAFK | Mutant of APR-Z1 | Charge–hydrophobicity balance drives apoptosis | MTT assay | A-375 | Skin Cancer | IC50 = 2.607 μM |
| dbacp07657 | AP1-Z3a | FLFSLIKHAIKGLISAFK | Mutant of APR-Z1 | Charge–hydrophobicity balance drives apoptosis | MTT assay | A-375 | Skin Cancer | Graph Figure 2B |
| dbacp07660 | AP1-Z3b | FLFSLIKHAISKLISAFK | Mutant of APR-Z1 | Charge–hydrophobicity balance drives apoptosis | MTT assay | A-375 | Skin Cancer | Graph Figure 2B |
| dbacp07663 | AP1-Z7 | FLFKLIKKAIKKLIKAFK | Mutant of APR-Z1 | Charge–hydrophobicity balance drives apoptosis | MTT assay | A-375 | Skin Cancer | Graph Figure 2B |
| dbacp07666 | AP1-Z9 | FLFKLIKKKIKKLIKKFK | Mutant of APR-Z1 | Charge–hydrophobicity balance drives apoptosis | MTT assay | A-375 | Skin Cancer | Graph Figure 2B |
| dbacp07803 | cT1 | KWCFRVCYRGICYRRCRG | Synthetic | Not Available | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 1.3 ± 0.1 µM |
| dbacp07804 | cT1 | KWCFRVCYRGICYRRCRG | Synthetic | Not Available | Resazurin dye assay | HT-144 | Skin Cancer | CC50 = 1.4 ± 0.1 µM |
| dbacp07805 | cT1 | KWCFRVCYRGICYRRCRG | Synthetic | Not Available | Resazurin dye assay | WM164 | Skin Cancer | CC50 = 2.7 ± 0.1 µM |
| dbacp07806 | cT1 | KWCFRVCYRGICYRRCRG | Synthetic | Not Available | Resazurin dye assay | MDA-MB-435S | Skin Cancer | CC50 = 2.7 ± 0.3 µM |
| dbacp07810 | [R/K]cT1 | KWCFKVCYKGICYKKCKG | Synthetic | Not Available | Resazurin dye assay | WM164 | Skin Cancer | CC50 = 4.3 ± 0.3 µM |
| dbacp07811 | [R/K]cT1 | KWCFKVCYKGICYKKCKG | Synthetic | Not Available | Resazurin dye assay | MDA-MB-435S | Skin Cancer | CC50 = 3.5 ± 0.4 µM |
| dbacp07814 | [W2S]cT1 | KSCFRVCYRGICYRRCRG | Synthetic | Not Available | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 2.0 ± 0.1 µM |
| dbacp07815 | [W2S]cT1 | KSCFRVCYRGICYRRCRG | Synthetic | Not Available | Resazurin dye assay | HT-144 | Skin Cancer | CC50 = 3.0 ± 0.2 µM |
| dbacp07816 | [W2S]cT1 | KSCFRVCYRGICYRRCRG | Synthetic | Not Available | Resazurin dye assay | WM164 | Skin Cancer | CC50 = 3.9 ± 0.2 µM |
| dbacp07817 | [W2S]cT1 | KSCFRVCYRGICYRRCRG | Synthetic | Not Available | Resazurin dye assay | MDA-MB-435S | Skin Cancer | CC50 = 18.9 ± 0.9 µM |
| dbacp07820 | [Y8S-I11S]cT1 | KWCFRVCSRGSCYRRCRG | Synthetic | Not Available | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 17.3 ± 1.0 µM |
| dbacp07821 | [Y8S-I11S]cT1 | KWCFRVCSRGSCYRRCRG | Synthetic | Not Available | Resazurin dye assay | HT-144 | Skin Cancer | CC50 = 27.8 ± 2.2 µM |
| dbacp07822 | [Y8S-I11S]cT1 | KWCFRVCSRGSCYRRCRG | Synthetic | Not Available | Resazurin dye assay | WM164 | Skin Cancer | CC50 = 28.2 ± 2.0 µM |
| dbacp07824 | [R9S]cT1 | KWCFRVCYSGICYRRCRG | Synthetic | Not Available | Resazurin dye assay | MDA-MB-435S | Skin Cancer | CC50 = 5.3 ± 0.6 µM |
| dbacp07825 | [R14S]cT1 | KWCFRVCYRGICYSRCRG | Synthetic | Not Available | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 1.7 ± 0.1 µM |
| dbacp07826 | [R14S]cT1 | KWCFRVCYRGICYSRCRG | Synthetic | Not Available | Resazurin dye assay | HT-144 | Skin Cancer | CC50 = 2.3 ± 0.2 µM |
| dbacp07827 | [R14S]cT1 | KWCFRVCYRGICYSRCRG | Synthetic | Not Available | Resazurin dye assay | WM164 | Skin Cancer | CC50 = 2.7 ± 0.1 µM |
| dbacp07828 | [R14S]cT1 | KWCFRVCYRGICYSRCRG | Synthetic | Not Available | Resazurin dye assay | MDA-MB-435S | Skin Cancer | CC50 = 3.5 ± 0.3 µM |
| dbacp07830 | [R17S]cT1 | KWCFRVCYRGICYRRCSG | Synthetic | Not Available | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 1.8 ± 0.1 µM |
| dbacp07831 | [R17S]cT1 | KWCFRVCYRGICYRRCSG | Synthetic | Not Available | Resazurin dye assay | HT-144 | Skin Cancer | CC50 = 1.2 ± 0.1 µM |
| dbacp07832 | [R17S]cT1 | KWCFRVCYRGICYRRCSG | Synthetic | Not Available | Resazurin dye assay | WM164 | Skin Cancer | CC50 = 1.8 ± 0.1 µM |
| dbacp07833 | [R17S]cT1 | KWCFRVCYRGICYRRCSG | Synthetic | Not Available | Resazurin dye assay | MDA-MB-435S | Skin Cancer | CC50 = 4.5 ± 0.3 µM |
| dbacp07835 | [R9S-R14S-R17S]cT1 | KWCFRVCYSGICYSRCSG | Synthetic | Not Available | Resazurin dye assay | HT-144 | Skin Cancer | CC50 = 11.8 ± 0.9 µM |
| dbacp07836 | [R9S-R14S-R17S]cT1 | KWCFRVCYSGICYSRCSG | Synthetic | Not Available | Resazurin dye assay | WM164 | Skin Cancer | CC50 = 11.1 ± 0.9 µM |
| dbacp07838 | [G18K]cT1 | KWCFRVCYRGICYRRCRK | Synthetic | Not Available | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 1.0 ± 0.1 µM |
| dbacp07839 | [G18K]cT1 | KWCFRVCYRGICYRRCRK | Synthetic | Not Available | Resazurin dye assay | HT-144 | Skin Cancer | CC50 = 3.2 ± 0.1 µM |
| dbacp07840 | [G18K]cT1 | KWCFRVCYRGICYRRCRK | Synthetic | Not Available | Resazurin dye assay | WM164 | Skin Cancer | CC50 = 2.7 ± 0.2 µM |
| dbacp07843 | [I11F-G18K]cT1 | KWCFRVCYRGFCYRRCRK | Synthetic | Not Available | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 1.3 ± 0.1 µM |
| dbacp07844 | [I11F-G18K]cT1 | KWCFRVCYRGFCYRRCRK | Synthetic | Not Available | Resazurin dye assay | HT-144 | Skin Cancer | CC50 = 3.2 ± 0.1 µM |
| dbacp07845 | [I11F-G18K]cT1 | KWCFRVCYRGFCYRRCRK | Synthetic | Not Available | Resazurin dye assay | WM164 | Skin Cancer | CC50 = 2.9 ± 0.2 µM |
| dbacp07879 | Nubein6.8 | LKCNQLIPPFWKTCPKGKNLCYKMTMRAAPMVPVKRGCIDVCPKSSLLIKYMCCNTDKCN | Naja nubiae | DNA damage and apoptosis induction | MTT assay | A-375 | Skin Cancer | EC50 = 0.54 ± 0.04 μM |
| dbacp07953 | S-24-R2PLx | GIMDTVKNAAKNLAGQLLDKLKCSITAC | Synthetic Analogue of Ranatuerin-2PLx | R2PLx induces caspase-dependent apoptosis | MTT assay | MDA-MB-435S | Skin Cancer | IC50 = 179.00 µM |
| dbacp07986 | SmacN7-Arg8 fused peptide P4 | Ahx-AVPIAQK(KRRRRRRRRRE) | Synthetic | Apoptosis inducing | Cell Titer Blue Cell Viability assay | U-266 | Skin Cancer | Cell viability < 50% at 50 μM |
| dbacp07987 | SmacN7-Arg8 fused peptide P5 | Ahx-(KAVPIAQKE)RRRRRRRR | Synthetic | Apoptosis inducing | Cell Titer Blue Cell Viability assay | U-266 | Skin Cancer | Cell viability < 50% at 50 μM |
| dbacp07988 | SmacN7-Arg8 fused peptide P7 | Ahx-(KAVPIAQKE)GG(KRRRRRRRRE) | Synthetic | Apoptosis inducing | Cell Titer Blue Cell Viability assay | U-266 | Skin Cancer | Cell viability < 50% at 50 μM |
| dbacp08014 | Ec-LDP-hBD1 | MANCVVGYIGERCQYRDLKWWELRGGGGSGGGGSAPAFSVSPASGLSDGQSVSVSVSGAAAGETYYIAQCAPVGGQDACNPATATSFTTDASGAASFSFVVRKSYTGSTPEGTPVGSVDCATAACNLGAGNSGLDLGHVALTFGGGGGSGGGGSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCKLEHHHHHH | Synthetic | EGFR-targeted defensin induces mitochondrial apoptosis | CCK-8 assay | A-431 | Skin Cancer | IC50 = 1.8 μM |
| dbacp08045 | R11-NLS-pep8 | RRRRRRRRRRRIKKKRKWEASALVCIRLVTSSKPRTVa | NKp44 derived synthetic peptide | NKp44-pep8 inhibits PCNA function | PrestoBlue assay | B-16 | Skin Cancer | ED50 = 7.1 μM |
| dbacp08067 | Temporin-PE | FLPIVAKLLSGLL | Pelophylax kl. esculentus | Modulates membrane interactions | MTT assay | MDA-MB-435S | Skin Cancer | IC50 = 33.23 μM |
| dbacp08071 | temporin-PEa | FLYIVAKLLSGLL | Synthetic analog of Temporin-PE | Modulates membrane interactions | MTT assay | MDA-MB-435S | Skin Cancer | IC50 = 9.864 μM |
| dbacp08075 | temporin-PEb | FLPIVAKLLSGLLGRKKRRQRRR | Synthetic analog of Temporin-PE | Modulates membrane interactions | MTT assay | MDA-MB-435S | Skin Cancer | IC50 = 3.483 μM |
| dbacp08080 | APETx4 | GTTCYCGKTIGIYWFGKYSCPTNRGYTGSCPYFLGICCYPVD | Anthopleura elegantissima | Not Available | CellTox Green Dye assay | MDA-MB-435S | Skin Cancer | Green object count < 100 /mm2 at 20 μM |
| dbacp08167 | Bmattacin2 | Not Available | silkworm Bombyx mori | Not Available | MTS assay | A-375 | Skin Cancer | IC50 = 5.23 μM |
| dbacp08174 | Peptide - 1 | GF(A6c)G(A6c)KK(A6c)G(A6c)F(A6c)G(A6c)GKK(A6c)KKKK | Synthetic | Not Available | CellTiter-Glo assay | UACC-62 | Skin Cancer | IC50 = 2.6 µM |
| dbacp08186 | Peptide - 2 | GF(A6c)G(A6c)R(A6c)G(A6c)F(A6c)G(A6c)GR(A6c)RRRR | Synthetic | Not Available | CellTiter-Glo assay | UACC-62 | Skin Cancer | IC50 = 6.4 µM |
| dbacp08194 | Peptide - 3 | GF(A6c)G(A6c)Orn(A6c)G(A6c)F(A6c)G(A6c)GOrn(A6c)Orn-Orn- Orn- Orn | Synthetic | Not Available | CellTiter-Glo assay | UACC-62 | Skin Cancer | IC50 = 3.1 µM |
| dbacp08202 | Peptide - 4 | GF(A6c)G(A6c)Dab(A6c)G(A6c)F(A6c)G(A6c)GDab(A6c)Dab-Dab-Dab-Dab | Synthetic | Not Available | CellTiter-Glo assay | UACC-62 | Skin Cancer | IC50 = 1.9 µM |
| dbacp08210 | Peptide - 6 | GF(A5c)G(A5c)K(A5c)G(A5c)F(A5c)G(A5c)GK(A5c)KKKK | Synthetic | Not Available | CellTiter-Glo assay | UACC-62 | Skin Cancer | IC50 > 7.5 µM |
| dbacp08218 | Peptide - 7 | GF(A5c)G(A5c)R(A5c)G(A5c)F(A5c)G(A5c)GR(A5c)RRRR | Synthetic | Not Available | CellTiter-Glo assay | UACC-62 | Skin Cancer | IC50 > 7.5 µM |
| dbacp08226 | Peptide - 8 | GF(A6c)G(Tic)K(A6c)G(Tic)F(A6c)G(Tic)GK(Tic)KKKK | Synthetic | Not Available | CellTiter-Glo assay | UACC-62 | Skin Cancer | IC50 > 7.5 µM |
| dbacp08234 | Peptide - 9 | GF(A6c)G(Oic)K(A6c)G(Oic)F(A6c)G(Oic)GK(Oic)KKKK | Synthetic | Not Available | CellTiter-Glo assay | UACC-62 | Skin Cancer | IC50 > 7.5 µM |
| dbacp08242 | Peptide - 10 | GF(A5c)G(A6c)K(A5c)G(A6c)F(A5c)G(A6c)GK(A5c)KKKK | Synthetic | Not Available | CellTiter-Glo assay | UACC-62 | Skin Cancer | IC50 > 7.5 µM |
| dbacp08250 | Peptide - 11 | KKKKGF(A6c)G(A6c)K(A6c)G(A6c)F(A6c)G(A6c)GK(A6c) | Synthetic | Not Available | CellTiter-Glo assay | UACC-62 | Skin Cancer | IC50 = 6.4 µM |
| dbacp08319 | Sample Peptide 2 from US011339203B2 | FIGNLALSDLLAGVAYTANLLLKKRTLRKNDRKKR | Synthetic | Not Available | CCK-8 assay | A-2058 | Skin Cancer | Cell Viability = 0.2% at 25 μM |
| dbacp08330 | Sample Peptide 1 from EP3604345B1 | MQIPQAPWPVVWAVLQLGWRKKRTLRKNDRKKR | Synthetic | Not Available | CCK-8 / WST-8 | A-2058 | Skin Cancer | Cell Viability = 6.7% at 25 μM |
| dbacp08338 | Sample Peptide 3 from EP3604345B1 | MRIFAVFIFMTYWHLLNAKKRTLRKNDRKKR | Synthetic | Not Available | CCK-8 / WST-8 | A-2058 | Skin Cancer | Cell Viability = 87.5% at 25 μM |